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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic cataract
ncRNA name hsa-miR-30a-5p
ncRNA Category miRNA
Disease name diabetic cataract
Species Homo sapiens
Tissues/Cell_line lenses
Methods microarray, qRT-PCR, Western blot, immunohistochemistry, luciferase reporter assay
Expression pattern down-regulated
Functional description Overexpression of miR-30a-5p decreased SNAI1, a known modulator of EMT, and the expression of vimentin and alpha-SMA in our diabetic cataract model in vitro.
PubMed ID 28442786
Year 2017
Title MicroRNA-30a Regulation of Epithelial-Mesenchymal Transition in Diabetic Cataracts Through Targeting SNAI1.
Drug-related ncRNA NO

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