ncRNA name | hsa-miR-30a-5p |
ncRNA Category | miRNA |
Disease name | diabetic cataract |
Species | Homo sapiens |
Tissues/Cell_line | lenses |
Methods | microarray, qRT-PCR, Western blot, immunohistochemistry, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | Overexpression of miR-30a-5p decreased SNAI1, a known modulator of EMT, and the expression of vimentin and alpha-SMA in our diabetic cataract model in vitro. |
PubMed ID | 28442786 |
Year | 2017 |
Title | MicroRNA-30a Regulation of Epithelial-Mesenchymal Transition in Diabetic Cataracts Through Targeting SNAI1. |
Drug-related ncRNA | NO |
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